Post by Sandwich on Oct 5, 2004 21:26:15 GMT -5
The Normal Human Female as a Mosaic of X-Chromosome Activity
The idea that “the human female is generally a genetic mosaic, containing cells with a genetically active maternal X-chromosome and cells with a genetically active paternal X chromosome. The fixation of the role each chromosome is to play seems to occur at an early stage of embryonic development”. The study focuses on blood cells, with the implication that the embryo may get its erythroid progenitor cells from the activity of two different X chromosomes.
www.pubmedcentral.gov/pagerender.fcgi?artid=285481&pageindex=1#page
The idea that “the human female is generally a genetic mosaic, containing cells with a genetically active maternal X-chromosome and cells with a genetically active paternal X chromosome. The fixation of the role each chromosome is to play seems to occur at an early stage of embryonic development”. The study focuses on blood cells, with the implication that the embryo may get its erythroid progenitor cells from the activity of two different X chromosomes.
www.pubmedcentral.gov/pagerender.fcgi?artid=285481&pageindex=1#page